By Dr. David Samadi
Prostate cancer, the second leading cause of cancer and cancer death in American men, is a significant concern for men, but new medical advancements like prostate-specific membrane antigen (PSMA) PET imaging, are changing the game. This technology, approved by the FDA in 2020, uses a radioactive tracer called 68Ga-PSMA-11 to target and pinpoint prostate cancer cells. Here’s a closer look at how PSMA PET works and why it’s a breakthrough:
What is PSMA PET?
PSMA PET is a cutting-edge imaging technique designed specifically for prostate cancer detection. It relies on 68Ga-PSMA-11, an FDA-approved radioactive drug that binds to prostate cancer cells, making them visible during PET scans.
How Does PSMA PET Work?
During a PSMA PET scan, patients receive an injection of the radioactive tracer 68Ga-PSMA-11. This tracer attaches itself to PSMA proteins, which are found in high concentrations on prostate cancer tumors. The PET scan then detects these concentrated tracers, allowing doctors to accurately locate and assess the extent of prostate cancer.
What Makes PSMA PET Different?
Compared to traditional methods like fluciclovine PET, which uses synthetic radioactive amino acids, PSMA PET offers superior precision in detecting prostate cancer. It not only helps in planning targeted treatments but also excels in identifying cancer spread beyond the prostate.
Benefits of PSMA PET
PSMA PET is a game-changer for prostate cancer diagnosis and treatment planning:
- It’s FDA-approved and highly effective in detecting cancer that other imaging techniques might miss.
- Combining PSMA tracer with CT or MRI scans enhances diagnostic accuracy.
Who Should Consider PSMA PET?
PSMA PET is recommended for:
- Men newly diagnosed with prostate cancer and who are at risk of metastasis.
- Men who have previously undergone treatments like radiation or prostatectomy but show signs of cancer recurrence (rising PSA levels).
Preparation for a PSMA PET Scan
Before your scan:
- Follow a limited carbohydrate diet 24 hours prior.
- Fast (except water) for 6 hours before the procedure.
- Take routine medications unless advised otherwise.
- Arrive early for your appointment and complete the necessary forms.
During the PSMA PET Scan
- You’ll receive the 68Ga-PSMA-11 injection and wait about an hour before the scan.
- The procedure typically takes around 2 hours, with the scan lasting about 30 minutes.
PSMA PET imaging represents a significant advancement in prostate cancer care, providing more precise insights and better treatment strategies. This technology helps ensure men receive the most accurate diagnoses and effective treatments possible.
Dr. David Samadi is the Director of Men’s Health and Urologic Oncology at St. Francis Hospital in Long Island. He’s a renowned and highly successful board-certified Urologic Oncologist Expert and Robotic Surgeon in New York City, regarded as one of the leading prostate surgeons in the U.S., with a vast expertise in prostate cancer treatment and Robotic-Assisted Laparoscopic Prostatectomy. Dr. Samadi is a medical contributor to NewsMax TV and is also the author of The Ultimate MANual, Dr. Samadi’s Guide to Men’s Health and Wellness, available online both on Amazon and Barnes & Noble. Visit Dr. Samadi’s websites at robotic oncology and prostate cancer 911.