Medications Used In The Treatment Of BPH

Medications Used In The Treatment Of BPH

Treatment for mild to moderate symptoms of benign prostatic hyperplasia (BPH) is usually done through medication. As with all drugs, BPH medications can potentially cause any number of side effects. Each drug comes with benefits and risks. Your treatment will depend on your symptoms, the size of your prostate, and other health related issues. While there’s no medication that can cure your BPH, there are several options that can ease bothersome symptoms of the condition. Since everyone doesn’t respond to BPH drugs in the same way, if one medication doesn’t improve your symptoms or if it causes uncomfortable side effects, your doctor may recommend another drug. Always let your doctor know how you’re feeling. This can help them find the best treatment to help bring you much needed relief.

Types of BPH Medications

Alpha Blockers

Alpha blockers work by relaxing muscle fibers in the prostate and bladder neck muscles allowing for easier urination. Side effects of alpha blockers include: dizziness, fainting, headaches, lightheadedness and low blood pressure.

5-Alpha Reductase Inhibitors

5-alpha reductase inhibitors help to shrink the prostate gland by preventing hormonal changes that cause an enlarged prostate. This can improve urine flow and ease other BPH symptoms as well. Side effects of 5-alpha reductase inhibitors include: erectile dysfunction, lower sex drive and retrograde ejaculation


Anticholinergics Normally prescribed to treat an overactive bladder or incontinence, anticholinergics help by relaxing the muscles in the bladder and urinary tract. However it appears to be less effective than alpha blockers and 5-alpha reductase inhibitors. Side effects may include: dry mouth, constipation and drowsiness.

Combination Therapy

Combination therapy uses both alpha blockers and 5-alpha reductase inhibitors and is prescribed if one of the medications alone have not been effective. Combination therapy can also decrease the development of complications and the need for surgical intervention. Although taking both medications may work better to ease your symptoms, it may also carry a higher risk of side effects from one or both drugs.

Phosphodiesterase-5 (PDE-5) Inhibitors

Phosphodiesterase-5 (PDE-5) inhibitors these drugs are approved to treat erectile dysfunction (ED). Only one of these drugs, called tadalifil (Cialis), is also FDA-approved to help relieve BPH symptoms. Side effects can include: headache, indigestion, and back, muscle, or limb pain.

Dr. David Samadi | Robotic Prostate Surgeon

About is a resource created by Dr. David Samadi in order to raise awareness and get more men to receive prostate cancer treatment. The information is strictly general and you should always discuss with your doctor issues concerning your health.


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