Could Gout Contribute to Erectile Dysfunction?

By Dr. David Samadi

Erectile dysfunction (ED) can be a troubling issue for many men, and recent research suggests that those with gout may face an increased risk. Studies have shown that men with gout may have an increased likelihood of experiencing erectile dysfunction (ED). These findings suggest a potential link between high uric acid levels (hyperuricemia) and inflammation as distinct risk factors for this condition.

The Study Findings

One such study was conducted at the Health Improvement Network, a UK-based electronic medical record database. They compared 38,438 men with gout to 154,332 men without gout. Among the group with gout, there were 2,290 new cases of ED, while 8,447 ED cases were found in the comparison group. The results showed that men with gout had a 15% higher risk of developing ED. Furthermore, men receiving gout treatment saw their risk of ED increase by 29%.

These findings align with previous studies. For instance, a paper in The Journal of Rheumatology reported that 76% of men with gout had ED, compared to 51% of men without the condition. Another study from Taiwan, published in The European Journal of Internal Medicine, found that men with gout were 1.2 times more likely to develop ED than those without gout.

Understanding Gout and Its Link to ED

The most prevalent form of inflammatory arthritis is gout. Gout affects over 8 million Americans. While it is more common in men, women, particularly post-menopause, can also develop gout. The condition is caused by a buildup of uric acid, that develops as the body breaks down purines, found naturally in cells and certain foods. When the kidneys cannot eliminate excess uric acid, it crystallizes in joint cartilage, causing intense pain and inflammation.

The connection between gout and ED may stem from depositing monosodium urate crystals in the joints, triggering inflammation and swelling. Gout is also frequently associated with cardiovascular risk factors, which are similarly linked to ED. Men with gout are more likely to have conditions such as high blood pressure and cholesterol, both of which are common in men with ED.

Other Contributing Factors to ED

In addition to gout, there are several other potential causes of ED:

  • Diabetes: Approximately 50% of men with diabetes also have ED. Chronically elevated blood glucose that is not well-managed can damage nerves and reduce blood flow, leading to erectile problems.
  • Obesity: Excess body weight often results in high cholesterol and clogged arteries, impeding blood flow to the penis.
  • Substance Use: Alcohol, smoking, and drug abuse can damage the brain and heart, affecting the signals and blood flow needed for an erection.
  • Medications: Certain medications used to treat blood pressure, or antihistamines, antidepressants, tranquilizers, and appetite suppressants, have been known to be linked to ED. 

Take Action

All men with gout and are experiencing ED, should talk to their doctor. It’s always important to bring up ED in those conversations which inadvertently can also improve your overall health status, including reducing your risk of heart disease and other related conditions. Knowing that there can be a link between gout and ED helps men take control of their health and to seek appropriate treatment.

 

Dr. David Samadi is the Director of Men’s Health and Urologic Oncology at St. Francis Hospital in Long Island. He’s a renowned and highly successful board-certified Urologic Oncologist Expert and Robotic Surgeon in New York City, regarded as one of the leading prostate surgeons in the U.S., with a vast expertise in prostate cancer treatment and Robotic-Assisted Laparoscopic Prostatectomy.  Dr. Samadi is a medical contributor to NewsMax TV and is also the author of two books, Prostate Cancer, Now What? A Practical Guide to Diagnosis, Treatment, and Recovery, and The Ultimate MANual, Dr. Samadi’s Guide to Men’s Health and Wellness, available online both on Amazon and Barnes & Noble. Visit Dr. Samadi’s websites at robotic oncology and prostate cancer 911. 

 

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